LibraryLiterature Review and Research Question Formulation

Literature Review and Research Question Formulation

Learn about Literature Review and Research Question Formulation as part of Advanced Biomedical Engineering and Medical Device Research

Mastering Literature Reviews and Research Questions in Biomedical Engineering

Embarking on a biomedical engineering capstone project or venturing into medical device research requires a strong foundation in understanding existing knowledge and defining a clear research direction. This module will guide you through the critical processes of conducting a comprehensive literature review and formulating a precise, impactful research question.

The Art and Science of Literature Review

A literature review is more than just summarizing existing papers; it's a critical synthesis of current knowledge, identifying gaps, controversies, and emerging trends in your field. For biomedical engineers, this means understanding the state-of-the-art in medical devices, biological systems, and clinical applications.

A literature review maps the existing landscape of your research topic.

It involves systematically searching, evaluating, and synthesizing relevant scholarly literature to understand what is already known about a subject. This process helps identify research gaps and informs the development of your own research question.

The process typically begins with identifying keywords related to your project. You'll then use academic databases (like PubMed, IEEE Xplore, Scopus, Web of Science) to find relevant articles, patents, and conference proceedings. Critically evaluate the sources for their relevance, methodology, and impact. Organize your findings thematically, noting key findings, methodologies, limitations, and unanswered questions. This synthesis forms the backbone of your understanding and guides your subsequent research.

Formulating a Powerful Research Question

Your research question is the compass that directs your entire project. In biomedical engineering, a well-formulated question is specific, measurable, achievable, relevant, and time-bound (SMART), and it addresses a genuine problem or gap identified in your literature review.

What are the key characteristics of a strong research question in scientific research?

A strong research question is specific, focused, researchable, relevant, and often addresses a gap in existing knowledge.

Consider the 'PICO' framework (Patient/Population, Intervention, Comparison, Outcome) or 'PEO' (Population, Exposure, Outcome) as helpful starting points, especially when dealing with clinical applications or device efficacy.

A well-defined research question acts as a funnel, narrowing down a broad topic into a manageable and answerable inquiry. For instance, instead of 'How can we improve prosthetics?', a better question might be 'What is the effect of proprioceptive feedback integration on gait stability in transtibial amputees using a novel robotic prosthetic ankle?' This specificity allows for targeted literature searches and experimental design.

📚

Text-based content

Library pages focus on text content

Connecting Literature Review to Research Questions

The iterative process of literature review and research question formulation is crucial. As you read, you'll refine your initial ideas. Conversely, a nascent research question can guide your literature search, making it more efficient. Look for areas where current research is inconclusive, contradictory, or has not yet explored a particular aspect relevant to medical device innovation or biological system understanding.

Think of your literature review as building a detailed map of the scientific territory. Your research question is the specific destination you aim to reach on that map, a place that hasn't been fully explored.

For biomedical engineering projects, consider the translational aspect: how does your research question bridge the gap between basic science and clinical application or device development? What is the potential impact on patient care or medical technology?

Practical Steps for Your Project

  1. Brainstorm: Identify broad areas of interest within biomedical engineering.
  2. Preliminary Search: Conduct initial searches to gauge the existing literature.
  3. Refine Topic: Narrow down your focus based on interest and literature availability.
  4. Systematic Search: Develop a comprehensive search strategy using relevant databases and keywords.
  5. Evaluate Sources: Critically assess the quality and relevance of identified literature.
  6. Synthesize Findings: Organize and summarize the key themes, gaps, and controversies.
  7. Formulate Question: Draft a clear, focused, and researchable question based on identified gaps.
  8. Iterate: Refine your question and search strategy as needed.
What is the primary purpose of a literature review in a capstone project?

To understand the existing knowledge, identify research gaps, and inform the development of a research question.

Learning Resources

PubMed Central (PMC) - National Institutes of Health(documentation)

Access a vast archive of full-text biomedical and life sciences journal literature, essential for literature reviews in BME.

IEEE Xplore Digital Library(documentation)

A premier source for research in electrical engineering, computer science, and electronics, crucial for many BME device-related topics.

Scopus - Elsevier(documentation)

A large abstract and citation database of peer-reviewed literature, offering broad coverage across scientific disciplines.

Web of Science - Clarivate Analytics(documentation)

A comprehensive citation index that provides access to a wide range of scholarly research across many fields.

How to Write a Literature Review - University of Toronto Libraries(tutorial)

A practical guide detailing the steps and strategies for conducting an effective literature review.

Developing a Research Question - University of British Columbia(tutorial)

Provides clear guidance and examples on how to formulate strong, focused research questions.

The PICO Question: A Key to Effective Information Retrieval - Journal of the Medical Library Association(paper)

Explains the PICO framework, a valuable tool for structuring clinical and biomedical research questions.

Writing a Strong Research Question - University of California, Berkeley(documentation)

A concise PDF document offering tips and criteria for crafting effective research questions.

Systematic Reviews: What are they? - Cochrane(documentation)

An overview of systematic reviews, a rigorous form of literature synthesis often used in health sciences.

Biomedical Engineering Society (BMES) - Resources(documentation)

The official society for biomedical engineering, offering access to publications, conferences, and career resources relevant to project development.